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Antigenic Specificity | CDH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cadherins are a superfamily of transmembrane glycoproteins that contain cadherin repeats of approximately 100 residues in their extracellular domain. Cadherins mediate calcium-dependent cell-cell adhesion and play critical roles in normal tissue development (1). The classic cadherin subfamily includes N-, P-, R-, B-, and E-cadherins, as well as about ten other members that are found in adherens junctions, a cellular structure near the apical surface of polarized epithelial cells. The cytoplasmic domain of classical cadherins interacts with beta-catenin, gamma-catenin (also called plakoglobin), and p120 catenin. beta-catenin and gamma-catenin associate with alpha-catenin, which links the cadherin-catenin complex to the actin cytoskeleton (1, |
Immunogen | Immunogen: A synthetic peptide of human CDH2 Observed Molecular Weight: 100kDa |
Other Names | [CDHN; NCAD; CD325; CDw325; N-Cadherin] |
Gene, Accession # | [CDH2], Gene ID: 1000, NCBI: P19022.4 |
Catalog # | MBS2519605 |
Price | $150, $225, $360 |
Order / More Info | CDH2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |