Edit |   |
---|---|
Antigenic Specificity | PGP9.5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total PGP9.5 protein. Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.Diana L. Mandelker, Cancer Res., Jun 2005; 65: 4963 - 4968. Taiji Yamazaki, Clin. Cancer Res., Jan 2002; 8: 192. Ekmel Tezel, Clin. Cancer Res., Dec 2000; 6: 4764. Kenji Hibi, Am. J. Pathol., Sep 1999; 155: 711. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human PGP9. |
Other Names | [UCH-L1; neuron cytoplasmic protein 9.5; ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin thiolesterase L1] |
Gene, Accession # | [PGP9.5], Gene ID: 7345, NCBI: NP_004172.2, UniProt: P09936 |
Catalog # | MBS9409956 |
Price | $200, $255 |
Order / More Info | PGP9.5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |