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Antigenic Specificity | RAC1 |
Clone | [1301CT276.121.104] |
Host Species | Mouse |
Reactive Species | human, rat (predicted reactivity: bovine, mouse) |
Isotype | IgG2b |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from human. Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates |
Immunogen | n/a |
Other Names | [Ras-related C3 botulinum toxin substrate 1; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1; RAC1; TC25] |
Gene, Accession # | [RAC1], Gene ID: 5879, NCBI: NP_008839.2, UniProt: P63000 |
Catalog # | MBS9200589 |
Price | $165, $370 |
Order / More Info | RAC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Didsbury J.,et al.J. Biol. Chem. 264:16378-16382(1989). Drivas G.T.,et al.Mol. Cell. Biol. 10:1793-1798(1990). Matos P.,et al.Biochem. Biophys. Res. Commun. 277:741-751(2000). Jordan P.,et al.Oncogene 18:6835-6839(1999). Schnelzer A.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases. |