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Antigenic Specificity | PI 3-Kinase p85alpha (Phospho Tyr607) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, chicken |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PI 3-kinase p85alpha (Y607) Polyclonal Antibody detects endogenous levels of PI 3-kinase p85alpha protein only when phosphorylated at Y607. Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1 results in four transcript variants encoding different isoforms. |
Immunogen | Immunogen: Synthesized peptide derived from human PI 3-kinase p85alpha around the phosphorylation site of Y607 |
Other Names | [Rabbit PI 3-kinase p85alpha (phospho Tyr607); PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alph] |
Gene, Accession # | Gene ID: 5295, NCBI: NP_001229395.1, UniProt: P27986 |
Catalog # | MBS9701234 |
Price | $130, $220, $325 |
Order / More Info | PI 3-Kinase p85alpha (Phospho Tyr607) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |