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Antigenic Specificity | PSD95 |
Clone | [6G6] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, bovine |
Isotype | IgG2a |
Format | Protein G purified |
Size | 0.025 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Microarray (AM) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~100kDa. An additional protein of >100kDa is also detected. Additional cross-reactive bands are detected at ~75kDa and 50kDa in rat and mouse samples. Postsynaptic Density protein 95 (PSD95), also known as Synapse associated protein 90kDa, is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. PSD95 is a scaffolding protein and is involved in the assembly and function of the postsynaptic density complex (1). These family members consist of an N-terminal variable segment followed by three amino-terminal PDZ domains, an upstream SH3 domain and an inactive carboxyl-terminal guanylate kinase (GK) domain. The first and second PDZ domain localize NMDA receptors and K+ channels to synapses, and the third binds |
Immunogen | Immunogen: Recombinant rat PSD-95 Immunogen Species: Rat |
Other Names | [Mouse Rat PSD95 IgG2a; PSD 95, Clone 6G6; PSD 95; PSD-95; DLG4; SAP90; Synapse-associated protein 90; Postsynaptic density protein 95; Disks large homolog 4] |
Gene, Accession # | [PSD95], Gene ID: 29495, NCBI: NP_062567.1, UniProt: P31016 |
Catalog # | MBS8001879 |
Price | $230 |
Order / More Info | PSD95 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Chetkovich D.M., Bunn R.C., Kuo S.H., Kawasaki Y., Kohwi M., and Bredt D.S. (2002) J Neurosci. 22(15): 6415-25. 2. Cao J., Viholainen J.I., Dart C., Warwick H.K., Levland M.L. and Courtney M.J. (2005) J Cell Biol. 168(1): 117-26. 3. Kennedy M. (1997) Trends in Neurosci. 6: 264-268. 4. Irie M. et al. (1997) Science 277(5331): 1511-5. 5. Cai C. et al. (2006) J Biol Chem. 281: 4267-73. 6. Yao W.D. et al. (2004) Neuron 41: 625-38. 7. Cline H. (2005) Curr Biol. 15: R203-5. |