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Antigenic Specificity | Rab25 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rab25 antibody detects endogenous levels of total Rab25. Description: Members of the Ras-related superfamily of GTP binding proteins, which includes Ras, Rho, Rab and ARF subfamilies, exhibit 30-50% similarity with Ras p21. Rab proteins play an important role for either in endocytosis or in biosynthetic protein transport. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% similar to Rab proteins, is associated with secretory vesicles. Rab proteins located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions.Function: I |
Immunogen | Immunogen: Purified recombinant fragment of human Rab25 expressed in E. Coli Subcellular Location: Cell Membrane. Cell Projection, Pseudopodium Membrane. Cytoplasmic Vesicle. Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips. Tissue Specificity: Expressed in ovarian epithelium (NOE) and breast tissue. Expressed in ovarian cancer; expression is increased relative to NOE cells. Expression in ovarian cancer is stage dependent, with stage III and stage IV showing higher l |
Other Names | [CATX 8; CATX-8; CATX8; RAB11C; RAB25; RAB25 member RAS oncogene family; RAB25_HUMAN; Ras related protein Rab 25; Ras-related protein Rab-25; RP11-336K24.10-001] |
Gene, Accession # | [Rab25], Gene ID: 57111, NCBI: NP_065120.2, UniProt: P57735 |
Catalog # | MBS9602658 |
Price | $235, $295, $370 |
Order / More Info | Rab25 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |