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Antigenic Specificity | IFITM3 (N-term) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IFITM3 antibody is generated from a mouse immunized with a recombinant protein KLH conjugated synthetic peptide between 1-133 amino acids from the N-terminal region of human IFITM3. IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) |
Immunogen | n/a |
Other Names | [Interferon-induced transmembrane protein 3; Dispanin subfamily A member 2b; DSPA2b; Interferon-inducible protein 1-8U; IFITM3] |
Gene, Accession # | [IFITM3], Gene ID: 10410, NCBI: NP_066362.2, UniProt: Q01628 |
Catalog # | MBS9217072 |
Price | $165, $370 |
Order / More Info | IFITM3 (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Lewin A.R.,et al.Eur. J. Biochem. 199:417-423 (1991). Everitt A.R.,et al.Nature 484:519-523 (2012). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45 (2004). Taylor T.D.,et al.Nature 440:497-500 (2006). |