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Antigenic Specificity | Phospho-STAT1 (S727) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, porcine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This STAT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S727 of human STAT1. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. |
Immunogen | n/a |
Other Names | [Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84; STAT1] |
Gene, Accession # | [STAT1], Gene ID: 6772, NCBI: NP_009330.1, UniProt: P42224 |
Catalog # | MBS9203264 |
Price | $165, $370 |
Order / More Info | Phospho-STAT1 (S727) Antibody from MYBIOSOURCE INC. |
Product Specific References | Garcin, D., et al., J. Virol. 78(16):8799-8811 (2004). Melen, K., et al., J. Med. Virol. 73(4):536-547 (2004). Klampfer, L., et al., J. Biol. Chem. 279(29):30358-30368 (2004). Marg, A., et al., J. Cell Biol. 165(6):823-833 (2004). Chim, C.S., et al., Blood 103(12):4630-4635 (2004). |