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Antigenic Specificity | Human Replication protein A 14 kDa subunit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref.7 Ref.9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. |
Immunogen | Immunogen: Recombinant human Replication protein A 14 kDa subunit protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30409 / sc-46623 / sc-46507 / sc-30411 |
Other Names | [Replication factor A protein 3.RPA3; REPA3; RPA14], [RPA3; RPA3; REPA3; RP-A p14; REPA3; RPA14; RP-A p14; RF-A protein 3] |
Gene, Accession # | Gene ID: 6119, NCBI: NP_002938.1, UniProt: P35244 |
Catalog # | MBS719641 |
Price | $160, $235 |
Order / More Info | Human Replication protein A 14 kDa subunit Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |