Edit |   |
---|---|
Antigenic Specificity | PA2G4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isof |
Immunogen | Immunogen: Recombinant human Proliferation-associated protein 2G4 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68478 / sc-292466 / sc-133531 |
Other Names | [Proliferation-associated protein 2G4; PA2G4; EBP1; Cell cycle protein p38-2G4 homolog; hG4-1; ErbB3-binding protein 1], [PA2G4; PA2G4; EBP1; HG4-1; p38-2G4; EBP1; hG4-1] |
Gene, Accession # | [PA2G4], Gene ID: 5036, NCBI: NP_006182.2, UniProt: Q9UQ80 |
Catalog # | MBS1493986 |
Price | $160, $235 |
Order / More Info | PA2G4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |