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Antigenic Specificity | UNG2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of UNG2 are known to exist; this antibody will only detect the longer isoform. UNG2 antibody is predicted to not cross-react with UNG1. UNG2 Antibody: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promoters and alternative splicing. UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from DNA that arise through either misincorporation during replication or cytosine deamination. UNG2 can also be bound by the HIV-1 integrase and incorporated into the virion particle, suggesting that it is required to remove uracils from the viral genome. As the intrinsic antiviral protein APOBEC3G g |
Immunogen | Immunogen: UNG2 antibody was raised against a 17 amino acid peptide near the amino terminus of human UNG2. Buffer: UNG2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [UNG2; DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15; DGU; Uracil-DNA glycosylase; uracil-DNA glycosylase], [UNG; UNG; DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15;] |
Gene, Accession # | [UNG], Gene ID: 7374, NCBI: NP_550433, UniProt: P13051 |
Catalog # | MBS153524 |
Price | $375 |
Order / More Info | UNG2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |