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Antigenic Specificity | ZAP-70 (Phospho Tyr319) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-ZAP-70 (Y319) Polyclonal Antibody detects endogenous levels of ZAP-70 protein only when phosphorylated at Y319. ZAP70 (zeta chain of T cell receptor associated protein kinase 70) encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in ZAP70 cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absenc |
Immunogen | Immunogen: Synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y319 |
Other Names | [Rabbit ZAP-70 (phospho Tyr319); ZAP70; SRK; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase] |
Gene, Accession # | [ZAP-70], Gene ID: 7535, NCBI: NP_001070.2, UniProt: P43403 |
Catalog # | MBS9707152 |
Price | $130, $220, $325 |
Order / More Info | ZAP-70 (Phospho Tyr319) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |