Edit |   |
---|---|
Antigenic Specificity | Human CD44v3-v10 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen, Immunohistology Paraffin* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item specifically recognises epitopes encoded by exons v3-v10 on the variant portion of human CD44. . . CD44 is a ubiquitously expressed type 1 transmembrane glycoprotein and proteoglycan, otherwise known as phagocytic glycoprotein 1 (pgp 1), which acts as a receptor for the major extracellular matrix component hyaluronate, and also binds other ligands including collagen and matrix metalloproteinases (MMPs). . . CD44 is known to play a role in cell-cell interactions, cell adhesion, the activation and homing of lymphocytes, cell migration, haematopoiesis and metastasis, and exists as a number of isoforms generated by the alternative RNA splicing of at least 10 variant exons (CD44v). MBS222952 specifically recognises epitopes encoded |
Immunogen | Immunogen: Recombinant human CD44v3-v10 Histology Positive Control Tissue: Breast carcinoma and colon adenocarcinoma Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human CD44v3-v10 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [CD44 antigen isoform 1; CD44 antigen; CD44 antigen; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; epican; extracellular matrix receptor III; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; homing function and Indian blood group system; hyaluronate receptor; phagocytic glycoprotein 1; CD44 molecule (Indian blood group); CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD_antigen: CD44], [CD44; CD44; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; LHR; MDU2; MDU3; MIC4; ECMR-III; PGP-1; PGP-I] |
Gene, Accession # | [CD44v3-v10], Gene ID: 960, NCBI: NP_000601.3, UniProt: P16070 |
Catalog # | MBS222952 |
Price | $550 |
Order / More Info | Human CD44v3-v10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |