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Antigenic Specificity | STAT3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this prote |
Immunogen | Immunogen: STAT3 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human STAT3, identical to the related rat and Rabbit sequences, as the immunogen |
Other Names | [Affinity Purified Rabbit STAT3; STAT3; STAT3; STAT3; Signal transducer and activator of transcription 3; STAT-3; FLJ20882; STAT 3; STAT 3; APRF; MGC16063; STAT-3] |
Gene, Accession # | [STAT3], Gene ID: 6774 |
Catalog # | MBS5312591 |
Price | $345 |
Order / More Info | STAT3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |