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Antigenic Specificity | CHST14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CHST14 antibody detects endogenous levels of total CHST14. Function: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1, 4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in-IdoUA-GalNAc-IdoUA-than in-GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. Appears to have an important role in the formation of t |
Immunogen | Immunogen: A synthesized peptide derived from human CHST14 Subcellular Location: Golgi Apparatus Membrane. Tissue Specificity: Widely expressed. Expressed at high level in pituitary gland, placenta, uterus and thyroid. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Sheep, Dog Similarity: Pig (100%), Zebrafish (100%), Bovine (91%), Sheep (91%), Dog (91%) |
Other Names | [2600016L03Rik; ATCS; Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 14; Carbohydrate sulfotransferase 14; CHST14; CHSTE_HUMAN; D4ST-1; D4st1; Dermatan 4-sulfotransferase 1; hD4ST1; RP23-286G12.2; UNQ1925/PRO4400] |
Gene, Accession # | [CHST14], Gene ID: 113189, NCBI: NP_569735.1, UniProt: Q8NCH0 |
Catalog # | MBS9609648 |
Price | $240, $280 |
Order / More Info | CHST14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |