Edit |   |
Antigenic Specificity | PSD95 |
Clone | [6G6] |
Host Species | Mouse |
Reactive Species | mouse, rat, bovine, human |
Isotype | IgG2a kappa |
Format | PE-ATTO 594 conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects a ~100kDa protein corresponding to the molecular mass of PSD-95 on SDS PAGE immunoblots. An additional protein of >100kDa is also detected. Additional cross-reactive bands are detected at ~75kDa and 50kDa in rat and mouse samples. Scientific Background: Postsynaptic Density protein 95 (PSD95), also known as Synapse associated protein 90kDa, is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. PSD95 is a scaffolding protein and is involved in the assembly and function of the postsynaptic density complex (1). These family members consist of an N-terminal variable segment followed by three amino-terminal PDZ domains, an upstream SH3 domain and an inactive carboxyl-terminal guanylate kinas |
Immunogen | n/a |
Other Names | [PSD 95; PSD-95; DLG4; SAP90; Synapse-associated protein 90; Postsynaptic density protein 95; Disks large homolog 4], [Dlg4; Dlg4; Dlgh4; PSD95; Sap90; Dlgh4; Psd95; PSD-95; SAP-90; SAP90] |
Gene, Accession # | Gene ID: 29495, NCBI: NP_062567.1, UniProt: P31016 |
Catalog # | MBS800284 |
Price | $425 |
Order / More Info | PSD95 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Chetkovich D.M., Bunn R.C., Kuo S.H., Kawasaki Y., Kohwi M., and Bredt D.S. (2002) J Neurosci. 22(15): 6415-25. 2. Cao J., Viholainen J.I., Dart C., Warwick H.K., Levland M.L. and Courtney M.J. (2005) J Cell Biol. 168(1): 117-26. 3. Kennedy M. (1997) Trends in Neurosci. 6: 264-268. 4. Irie M. et al. (1997) Science 277(5331): 1511-5. 5. Cai C. et al. (2006) J Biol Chem. 281: 4267-73. 6. Yao W.D. et al. (2004) Neuron 41: 625-38. 7. Cline H. (2005) Curr Biol. 15: R203-5. |