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Antigenic Specificity | SIGLEC8 (N-term), 94-122 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SIGLEC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human SIGLEC8. Sialic acid-binding immunoglobulin (Ig)-like lectins, orSIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1transmembrane proteins each having a unique expression pattern,mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-likesubgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptortyrosine-based inhibitory motif, or ITIM (see MIM 604964), and amotif homologous to one identified in signaling lymphocyteactivation molecule (SLAM; MIM 603492) that mediates an |
Immunogen | n/a |
Other Names | [Sialic acid-binding Ig-like lectin 8; Siglec-8; Sialoadhesin family member 2; SAF-2; SIGLEC8; SAF2] |
Gene, Accession # | [SIGLEC8], Gene ID: 27181, NCBI: NP_055257.2, UniProt: Q9NYZ4 |
Catalog # | MBS9214391 |
Price | $165, $370 |
Order / More Info | SIGLEC8 (N-term), 94-122 Antibody from MYBIOSOURCE INC. |
Product Specific References | Gao, P.S., et al. Eur. J. Hum. Genet. 18(6):713-719(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Hudson, S.A., et al. J. Pharmacol. Exp. Ther. 330(2):608-612(2009) Bochner, B.S. Clin. Exp. Allergy 39(3):317-324(2009) von Gunten, S., et al. Autoimmun Rev 7(6):453-456(2008) |