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Antigenic Specificity | TRAF-6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat, mouse, human |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human TRAF6 is a 522 amino acid protein. The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases. TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can pr |
Immunogen | Immunogen Information: A synthetic peptide of human TRAF-6 (amino acids 451-469 DAKPELLAFQRPTIPRNPK) was used as immunogen for this antibody |
Other Names | [TRAF6; RNF85; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85; to TRAF-6; TRAF-6; TRAF-6], [TRAF6; TRAF6; RNF85; MGC:3310; RNF85] |
Gene, Accession # | [TRAF6], Gene ID: 7189, NCBI: Q9Y4K3.1, UniProt: Q9Y4K3 |
Catalog # | MBS668820 |
Price | $270 |
Order / More Info | TRAF-6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |