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Antigenic Specificity | M6PR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: M6PR antibody detects endogenous levels of total M6PR. Function: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.Subunit Structure: Homodimer. Binds GGA1, GGA2 and GGA3.Similarity: The extracellular domain is homologous to the repeating units (of approximately 147 AA) of the cation-independent mannose 6-phosphate receptor. |
Immunogen | Immunogen: A synthesized peptide derived from human M6PR Subcellular Location: Lysosome Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (89%), Dog (100%) |
Other Names | [46 kDa mannose 6 phosphate receptor; 46 kDa mannose 6-phosphate receptor; Cation dependent mannose 6 phosphate receptor; Cation dependent mannose 6 phosphate receptor precursor; Cation-dependent mannose-6-phosphate receptor; CD Man 6 P receptor; CD Man-6-P receptor; CD MPR; CD-M6PR; CD-MPR; FLJ32994; M6pr; M6PR protein; Man6PR; Mannose 6 phosphate receptor (cation dependent); Mannose 6 phosphate receptor; MPR 46; MPR46; MPRD; MPRD_HUMAN; Mr 46, 000 Man6PR; Small mannose 6 phosphate receptor; SMPR] |
Gene, Accession # | [M6PR], Gene ID: 4074, NCBI: NP_002346.1, UniProt: P20645 |
Catalog # | MBS9609671 |
Price | $240, $280 |
Order / More Info | M6PR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |