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Antigenic Specificity | Human CD196 |
Clone | [G034E3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | fluorescein (FITC) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCR6, also known as CD196, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the beta defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CC |
Immunogen | n/a |
Other Names | [CKRL3; CMKBR6; GPR29; STRL22; GPRCY4] |
Gene, Accession # | [CD196], Gene ID: 1235, NCBI: NP_113597.2, UniProt: P51684 |
Catalog # | MBS2559142 |
Price | $100, $125, $165 |
Order / More Info | Human CD196 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |