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Antigenic Specificity | c-Jun |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.2 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti c-Jun antibody recognizes c-Jun, also known as p39. The c-Jun transcription factor is encoded by the c-Jun oncogene and dimerizes with c-Fos, JDP and ATF family members to form the AP-1 transcription factor (Eferl and Wagner 2003). AP-1 is activated by a variety of stimuli including cytokines, stress and growth factors, and plays a critical role in cellular processes ranging from proliferation to apoptosis. c-Jun becomes phosphorylated on Serine 63 and Serine 73 by MAPK8 (SAPK/JNK) and PLK3, which regulate c-Jun transcription. c-Jun has been implicated in early tumor development, invasion and metastasis, and due to these findings has been identified as a target for cancer therapies. |
Immunogen | Immunogen: Peptide mapping to the amino terminus of mouse c-Jun |
Other Names | [c-Jun], [Jun; Jun; AP-1; Junc; c-jun; AP1; Jun A] |
Gene, Accession # | [Jun], Gene ID: 16476, NCBI: P05627.3, UniProt: P05627 |
Catalog # | MBS225056 |
Price | $375 |
Order / More Info | c-Jun Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |