c-Jun Antibody from MYBIOSOURCE INC.

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Antigenic Specificityc-Jun
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, human, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.2 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionRabbit anti c-Jun antibody recognizes c-Jun, also known as p39. The c-Jun transcription factor is encoded by the c-Jun oncogene and dimerizes with c-Fos, JDP and ATF family members to form the AP-1 transcription factor (Eferl and Wagner 2003). AP-1 is activated by a variety of stimuli including cytokines, stress and growth factors, and plays a critical role in cellular processes ranging from proliferation to apoptosis. c-Jun becomes phosphorylated on Serine 63 and Serine 73 by MAPK8 (SAPK/JNK) and PLK3, which regulate c-Jun transcription. c-Jun has been implicated in early tumor development, invasion and metastasis, and due to these findings has been identified as a target for cancer therapies.
ImmunogenImmunogen: Peptide mapping to the amino terminus of mouse c-Jun
Other Names[c-Jun], [Jun; Jun; AP-1; Junc; c-jun; AP1; Jun A]
Gene, Accession #[Jun], Gene ID: 16476, NCBI: P05627.3, UniProt: P05627
Catalog #MBS225056
Price$375
Order / More Infoc-Jun Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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