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Antigenic Specificity | OGG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [HMMH; MUTM; OGH1; HOGG1], [OGG1; OGG1; HMMH; MUTM; OGH1; HOGG1; MMH; MUTM; OGH1; AP lyase] |
Gene, Accession # | [OGG1], Gene ID: 4968, NCBI: O15527.2, UniProt: O15527 |
Catalog # | MBS127460 |
Price | $275, $430 |
Order / More Info | OGG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |