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Antigenic Specificity | SRRT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. D |
Immunogen | Immunogen: Recombinant human Serrate RNA effector molecule homolog protein (627-876aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162539 / sc-162540 / sc-135083 |
Other Names | [Arsenite-resistance protein 2; SRRT; ARS2; ASR2], [SRRT; SRRT; ARS2; ASR2; serrate; ARS2; ASR2] |
Gene, Accession # | [SRRT], Gene ID: 51593, NCBI: NP_001122324.1, UniProt: Q9BXP5 |
Catalog # | MBS1497177 |
Price | $120, $160 |
Order / More Info | SRRT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |