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Antigenic Specificity | IFM3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total IFM3 protein. IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human IFM3. |
Other Names | [IFM3; INIB; interferon-induced transmembrane protein 3; interferon-inducible protein 1-8U] |
Gene, Accession # | [IFM3], Gene ID: 10410, NCBI: NP_066362.2, UniProt: Q01628 |
Catalog # | MBS9409144 |
Price | $200, $255 |
Order / More Info | IFM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |