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Antigenic Specificity | GRIA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site |
Immunogen | Immunogen: Recombinant protein of human GRIA2 (NP 001077088.1). |
Other Names | [glutamate receptor 2 isoform 1; Glutamate receptor 2; glutamate receptor 2; glutamate ionotropic receptor AMPA type subunit 2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2] |
Gene, Accession # | [GRIA2], Gene ID: 2891, NCBI: NP_000817.2, UniProt: P42262 |
Catalog # | MBS8566111 |
Price | $280 |
Order / More Info | GRIA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |