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Antigenic Specificity | rat 72 kDa type IV collagenase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues (By similarity). |
Immunogen | Immunogen: Recombinant rat 72 kDa type IV collagenase protein(110-662AA) |
Other Names | [72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; Mmp2], [Mmp2; Mmp2; MMP-2] |
Gene, Accession # | Gene ID: 81686, NCBI: NP_112316.2, UniProt: P33436 |
Catalog # | MBS1493673 |
Price | $160, $235 |
Order / More Info | rat 72 kDa type IV collagenase Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |