HCLS1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | HCLS1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: HCLS1 Antibody detects endogenous levels of total HCLS1. HS1 (HCLS1, LckBP1, p75) is a protein kinase substrate that is expressed only in tissues and cells of hematopoietic origin (1, 2). HS1 contains four cortactin repeats and a single SH3 domain (2). This intracellular protein is phosphorylated following immune receptor activation, which promotes recruitment of HS1 to the immune synapse (3-5). Phosphorylation of HS1 is required to regulate actin dynamics and provide docking sites for many other signaling molecules, such as Vav1 and PLC gamma 1 (6). HS1 also plays an important role in platelet activation (7). |
| Immunogen | Immunogen: Recombinant protein of human HCLS1 |
| Other Names | [HS1; HCLS1; LckBP1; p75; CTTNL] |
| Gene, Accession # | [HCLS1], Gene ID: 3059, NCBI: NP_001278970.1, UniProt: P14317 |
| Catalog # | MBS8516358 |
| Price | $290 |
| Order / More Info | HCLS1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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