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Antigenic Specificity | CTRO |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CTRO protein. Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.Nagase T., DNA Res. 6:63-70(1999).Scherer S.E., Nature 440:346-351(2006).Gruneberg U., J. Cell Biol. 172:363-372(2006). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CTRO. |
Other Names | [Citron Rho-interacting kinase; CRIK; Rho-interacting; serine/threonine-protein kinase 21; CIT] |
Gene, Accession # | [CTRO], Gene ID: 11113, NCBI: NP_001193928.1, UniProt: O14578 |
Catalog # | MBS9413419 |
Price | $200, $255 |
Order / More Info | CTRO Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |