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Antigenic Specificity | Phospho-NCoA2 (Ser698/699) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-NCoA2 (Ser698/699) Antibody detects endogenous levels of NCoA2 only when phosphorylated at Ser698/699. Description: Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOC |
Immunogen | Immunogen: A synthesized peptide derived from human NCoA2 around the phosphorylation site of Ser698/699. |
Other Names | [bHLHe75; Class E basic helix-loop-helix protein 75; glucocorticoid receptor interacting protein 1; GRIP 1; GRIP1; hTIF2; MED1; MGC138808; NCoA 2; NCoA-2; Ncoa2; NCOA2_HUMAN; Nuclear receptor coactivator 2; Oncogene FGR; p160; SRC 2; src2; Steroid receptor coactivator 2; TIF 2; TIF2; Transcriptional intermediary factor 2] |
Gene, Accession # | [NCoA2], Gene ID: 10499, NCBI: NP_006531.1, UniProt: Q15596 |
Catalog # | MBS9610756 |
Price | $225, $280, $340 |
Order / More Info | Phospho-NCoA2 (Ser698/699) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |