NALP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNALP1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionNALP1 Antibody: NALP1 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. It contains a caspase recruitment domain (CARD) in addition to a NACHT domain and leucine rich repeat (LRR). This protein interacts strongly with caspase 2 and weakly with caspase 9, as well as with Apaf-1. Transient overexpression of this gene in cultured cells was sufficient to induce apoptosis. NALP1 mRNA and protein expression levels in myeloid leukemia cells are increased following CREB (cAMP-response element binding protein) activation, suggesting that NALP1 may contribute to modulate the response of these cells to pro-inflammatory stimuli. Multiple alternatively spliced transcript varian
ImmunogenImmunogen: NALP1 antibody was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human NALP1. Buffer: NALP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[NALP1; NAC; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S; KIAA0926; NAC; NACHT; LRR and PYD domains-containing protein 1; Caspase recruitment domain-containing protein 7; NLR family, pyrin domain containing 1], [NLRP1; NLRP1; NAC; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S; CARD7; DEFCAP; KIAA0926; NAC; NALP1]
Gene, Accession #[NLRP1], Gene ID: 22861, NCBI: AAG30288, UniProt: Q9C000
Catalog #MBS150260
Price$375
Order / More InfoNALP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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