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Antigenic Specificity | NALP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NALP1 Antibody: NALP1 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. It contains a caspase recruitment domain (CARD) in addition to a NACHT domain and leucine rich repeat (LRR). This protein interacts strongly with caspase 2 and weakly with caspase 9, as well as with Apaf-1. Transient overexpression of this gene in cultured cells was sufficient to induce apoptosis. NALP1 mRNA and protein expression levels in myeloid leukemia cells are increased following CREB (cAMP-response element binding protein) activation, suggesting that NALP1 may contribute to modulate the response of these cells to pro-inflammatory stimuli. Multiple alternatively spliced transcript varian |
Immunogen | Immunogen: NALP1 antibody was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human NALP1. Buffer: NALP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NALP1; NAC; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S; KIAA0926; NAC; NACHT; LRR and PYD domains-containing protein 1; Caspase recruitment domain-containing protein 7; NLR family, pyrin domain containing 1], [NLRP1; NLRP1; NAC; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S; CARD7; DEFCAP; KIAA0926; NAC; NALP1] |
Gene, Accession # | [NLRP1], Gene ID: 22861, NCBI: AAG30288, UniProt: Q9C000 |
Catalog # | MBS150260 |
Price | $375 |
Order / More Info | NALP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |