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Antigenic Specificity | MAS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for angiotensin 1-7. Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 246-325 of human MAS1 (NP 002368.1). |
Other Names | [MAS; MGRA] |
Gene, Accession # | [MAS1], Gene ID: 4142, NCBI: NP_002368.1, UniProt: P04201 |
Catalog # | MBS8547250 |
Price | $280 |
Order / More Info | MAS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |