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Antigenic Specificity | GluN1/NR1 NMDA |
Clone | [S308-48] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~105 kDa. The NMDA receptor (NMDAR), a glutamate receptor, is the predominant molecular device for controlling synaptic plasticity and memory function (1). The NMDA receptor forms a heterotetramer between two NR1 and two NR2 subunits (the subunits are also called glutamate-binding NMDA receptor subunits or GluN for short); two obligatory NR1 subunits and two regionally localized NR2 subunits. A related gene family of NR3 A and B subunits have an inhibitory effect on receptor activity. Multiple receptor isoforms with distinct brain distributions and functional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2 subunits. |
Immunogen | Immunogen: Fusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1 |
Other Names | [Mouse Rat GluN1/NR1 IgG1; GluN1/NR1 : APC/Cy7; NMDAR1; NMDA Receptor 1; NMDAR; NMDA1; GRIN1; Glutamate [NMDA] receptor subunit zeta-1; Glutamate receptor ionotropic N methyl D aspartate 1; MRD8; N methyl D aspartate receptor; N methyl D aspartate receptor channel subunit zeta 1; N methyl D aspartate receptor subunit NR1; NMD-R1; NMDA 1; NMDA R1; NMDZ1_HUMAN; NR1; GluN1] |
Gene, Accession # | [GluN1], Gene ID: 24408, NCBI: NP_001257531.1, UniProt: P35439 |
Catalog # | MBS8003154 |
Price | $510 |
Order / More Info | GluN1/NR1 NMDA Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Li F., and Tsien J.Z. (2009) New England J. Medicine. 361: 302-303. 2. Garcia-Gallo M., Renart J., Diaz-Guerra M. (2001) Biochem J. 356: 539-547. 3. Atlason P.T., Garside M.L., Meddows E., Whiting P., McIllhinney R.A.J. (2007) J Biol Chem. 282(35): 25299-25307. |