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Antigenic Specificity | FOXP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, chicken, horse, human, porcine, rat, rhesus monkey |
Isotype | n/a |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | One of the many immunotolerance mechanisms that the immune system has developed to distinguish between self and non-self antigens is regulatory T cells or Tregs. Several elegant experiments, using transgenic mice and retrovirus-mediated over expression studies, have led to the identification of FOXP3, a transcription factor, as a specific molecular marker essential for the development and function of Tregs. The primary evidence regarding the involvement of FOXP3 in the development of Tregs was provided in patients suffering from IPEX, a rare and fatal human autoimmune disease. The emergence of Tregs and the role of FOXP3 as a critical player in the negative control of various normal and pathological immune responses holds great promise for |
Immunogen | Immunogen: FOXP3 antibody was raised in Rabbit using a synthetic peptide corresponding to the exon 2 deletion site as the immunogen |
Other Names | [Affinity Purified Rabbit FOXP3; FOXP3; FOXP3; Forkhead Box P3 FOXP3; FOXP 3; FOXP-3; FOXP 3; FOXP-3] |
Gene, Accession # | [FOXP3], Gene ID: 50943 |
Catalog # | MBS5313085 |
Price | $375 |
Order / More Info | FOXP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |