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Antigenic Specificity | ARPP19 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ARPP19 antibody detects endogenous levels of total ARPP19. Function: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.Subunit Structure: Interacts (when phosphorylated at Ser-62) with PPP2R2D (By similarity). Interacts with SNCA.Post-translational Modifications: Phosphorylation at Ser-62 by GWL during mitosis is essential for interaction with PPP2R2D (PR55-delta) and subsequent inactivation of PP2A ( |
Immunogen | Immunogen: A synthesized peptide derived from human ARPP19 Subcellular Location: Cytoplasm. Tissue Specificity: Expression may be regulated by miR-451. Similarity: Belongs to the endo sulfine family. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%), Chicken (91%) |
Other Names | [ARP19_HUMAN; ARPP-19; Arpp19; cAMP-regulated phosphoprotein 19] |
Gene, Accession # | [ARPP19], Gene ID: 10776, NCBI: NP_001293120.1, UniProt: P56211 |
Catalog # | MBS9609642 |
Price | $240, $280 |
Order / More Info | ARPP19 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |