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Antigenic Specificity | Peroxiredoxin 5 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Peroxiredoxin-5, mitochondrial(PRDX5) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat. Background: PRDX5 (peroxiredoxin 5) also known as AOEB166, ACR1,B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10, is a member of the peroxiredoxin family and may play an antioxidant protective role in various tissues under nonpathologic conditions and during inflammatory processes. The PRDX5 gene is mapped to11q13.1. PRDX5 displays mitochondrial presequence features and has 3 cysteines implicated in antioxidant activity and a C-terminal SQL peroxisomal targeting sequence. Northern blot analysis revealed ubiquitous expression of a 1.0-kb PRDX5 transcript in tissues and cell line |
Immunogen | Immunogen: E Coli-derived human Peroxiredoxin 5 recombinant protein (Position: E66-D198). Human Peroxiredoxin 5 shares 91% amino acid (aa) sequence identity with both mouse and rat Peroxiredoxin 5. Ig Type: Rabbit IgG |
Other Names | [Peroxiredoxin-5; ACR 1; ACR1; Alu co repressor 1; Alu co-repressor 1; Alu corepressor 1; antioxidant enzyme B166; AOEB166; B166; liver tissue 2D-page spot 71B; MGC117264; MGC142283; MGC142285; mitochondrial; Peroxiredoxin 5 mitochondrial; Peroxiredoxin 5, mitochondrial; Peroxiredoxin V; Peroxiredoxin-5; Peroxiredoxin5; peroxisomal antioxidant enzyme; PLP; PMP 20; PMP20; PRDX 5; PRDX 6; PRDX5; PRDX5_HUMAN; PRDX6; Prx V; Prx-V; PRXV; SBBI10; thioredoxin peroxidase PMP20; Thioredoxin reductase; TPx type VI; peroxiredoxin 5], [PRDX5; PRDX5; PLP; ACR1; B166; PRXV; PMP20; PRDX6; prx-V; SBBI10; AOEB166; HEL-S-55; ACR1; AOEB166; Prx-V] |
Gene, Accession # | Gene ID: 25824, NCBI: NP_036226.1, UniProt: P30044 |
Catalog # | MBS177800 |
Price | $315 |
Order / More Info | Peroxiredoxin 5 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Budanov, A. V., Sablina, A. A., Feinstein, E., Koonin, E. V., Chumakov, P. M. Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science 304: 596-600, 2004. 2. Knoops, B., Clippe, A., Bogard, C., Arsalane, K., Wattiez, R., Hermans, C., Duconseille, E., Falmagne, P., Bernard, A. Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family. J. Biol. Chem. 274: 30451-30458, 1999. 3. Wang, M.-X., Wei, A., Yuan, J., Trickett, A., Knoops, B., Murrell, G. A. C. Expression and regulation of peroxiredoxin 5 in human osteoarthritis. FEBS Lett. 531: 359-362, 2002. |