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Antigenic Specificity | Lck |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Lck (phospho-Tyr505) antibody detects endogenous levels of Lck only when phosphorylated at tyrosine 505. This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding t |
Immunogen | Immunogen: The antibody was produced against synthesized phosphopeptide derived from human Lck around the phosphorylation site of tyrosine 505 (G-Q-YP-Q-P). |
Other Names | [Lck (Phospho-Tyr505)], [LCK; LCK; LSK; YT16; IMD22; p56lck; pp58lck] |
Gene, Accession # | [Lck], Gene ID: 3932, NCBI: AAA59503.1 |
Catalog # | MBS417475 |
Price | $325 |
Order / More Info | Lck Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |