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Antigenic Specificity | Bcl-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Bcl-2 family of apoptosis-related genes plays central roles in regulating apoptotic pathways (reviewed in Thomadaki and Scorilas, 2006). Regulation of cell death through apoptosis is critical for the maintenance of homeostasis, defense against infectious agents, and normal development. Bcl-2 family proteins regulate apoptosis primarily through the regulation of mitochondrial outer membrane permeability. In mammals, the family consists of both prosurvival (antiapoptotic) and proapoptotic (prodeath) members. Cellular homeostasis is thought to be dependent on a balance between the actions of prosurvival and proapoptotic proteins. Bcl-2 family proteins can be divided into 3 main subfamilies on the basis of their function and the content of |
Immunogen | Immunogen Information: A synthetic peptide of Bcl-2 protein (amino acids 67-86) was used as the immunogen for this antibody |
Other Names | [BCL2; Apoptosis regulator Bcl-2; to Bcl-2; Bcl-2; Bcl-2], [BCL2; BCL2; Bcl-2; PPP1R50] |
Gene, Accession # | [BCL2], Gene ID: 596, NCBI: P10415.2, UniProt: P10415 |
Catalog # | MBS668535 |
Price | $270 |
Order / More Info | Bcl-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |