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Antigenic Specificity | CEP57 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining |
Immunogen | Immunogen: Recombinant protein of human CEP57 (NP 055494.2). |
Other Names | [centrosomal protein of 57 kDa isoform b; Centrosomal protein of 57 kDa; centrosomal protein of 57 kDa; centrosomal protein 57; FGF2-interacting protein; Testis-specific protein 57; Translokin] |
Gene, Accession # | [CEP57], Gene ID: 9702, NCBI: NP_001230705.1, UniProt: Q86XR8 |
Catalog # | MBS8573800 |
Price | $280 |
Order / More Info | CEP57 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |