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Antigenic Specificity | Human IL-8 |
Clone | [B-K8] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa light chain |
Format | no preservative |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), ELISA, Functional Assay |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognises both natural and recombinant human IL-8. Interleukin 8 (IL-8) or CXCL8, Monocyte-Derived Neutrophil Chemotactic Factor (MDNCF), Neutrophil Activating Factor (NAF) and NAD-P1 is a chemokine secreted by monocytes, macrophages and endothelial cells. IL-8 chemoattracts and activates neutrophils. The predominant form of IL-8 is a 8.4kDa protein containing 72 amino acid residues, which includes five additional N-Terminal amino-acids. IL-8 contains the four conserved cysteine residues present in CXC chemokines and also contains the ``ELR'' motif common to CXC chemokines that binds to CXCR1 and CXCR2. Data indicate that IL-8 may participate in the pathogenesis of rheumatoid arthritis via the induction of neutrophil-mediated cartilage damag |
Immunogen | Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells. Immunization: Recombinant human IL-8 |
Other Names | [IL-8], [IL8; CXCL8; CXCL8; AMCF-I; IL8; IL-8; AMCF-I] |
Gene, Accession # | [IL-8], Gene ID: 396880, NCBI: NP_999032.1, UniProt: P26894 |
Catalog # | MBS335032 |
Price | $530 |
Order / More Info | Human IL-8 Antibody from MYBIOSOURCE INC. |
Product Specific References | Schruefer et.al Am J Physiol Heart Ciec Physiol 2005 |