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Antigenic Specificity | TFIP8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TFIP8 protein. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.Horrevoets A.J.G., Blood 93:3418-3431(1999).Kumar D., J. Biol. Chem. 275:2973-2978(2000).You Z., J. Biol. Chem. 276:26398-26404(2001). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TFIP8. |
Other Names | [Tumor necrosis factor; alpha-induced protein 8; Head and neck tumor and metastasis-related protein; TNF-induced protein GG2-1; SCC-S2] |
Gene, Accession # | [TFIP8], Gene ID: 25816, NCBI: NP_001071122.1, UniProt: O95379 |
Catalog # | MBS9403866 |
Price | $200, $255 |
Order / More Info | TFIP8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |