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Antigenic Specificity | JNK1/2/3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 400 mug/mL |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1alpha1, JNK1beta1, JNK2alpha1, JNK2beta1 and JNK3alpha1, which represent the p46 isoforms, and JNK1alpha2, JNK1beta2, JNK2alpha2, JNK2beta2 and JNK3beta2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and ransformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 an |
Immunogen | Immunogen: KLH conjugated synthetic peptide corresponding to human JNK1 |
Other Names | [MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi] |
Gene, Accession # | [JNK1/2/3], Gene ID: 26419, NCBI: NP_057909.1, UniProt: Q91Y86 |
Catalog # | MBS2556361 |
Price | $150, $225, $360 |
Order / More Info | JNK1/2/3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |