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Antigenic Specificity | MAPK10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using MAPK10 antibody. The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, growth factors and GPCR agonists (1-6). As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7. Upon activation, MKKs phosphorylate and activate the SAPK/JNK kinase (2). Stress signals are delivered to this cascade by small GTPases of the Rho family (Rac, Rho, cdc42) (3). Both Rac1 an |
Immunogen | Immunogen: Recombinant protein of human MAPK10 |
Other Names | [MAPK10 protein; Mitogen-activated protein kinase 10; mitogen-activated protein kinase 10; mitogen-activated protein kinase 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; Stress-activated protein kinase JNK3; c-Jun N-terminal kinase 3], [MAPK10; MAPK10; JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK; JNK3; JNK3A; PRKM10; SAPK1B; MAP kinase 10; MAPK 10; SAPK1b] |
Gene, Accession # | [MAPK10], Gene ID: 5602, NCBI: AAH51731.1 |
Catalog # | MBS419990 |
Price | $385 |
Order / More Info | MAPK10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |