Histone H3 Phospho Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHistone H3 Phospho
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size5 Control Slides, 3 ml (Prediluted), 0.1 mL (Concentrate)
Concentrationn/a
Applicationsn/a
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DescriptionPhosphohistone-H3 is one of the five main histone proteins involved in the struc-ture of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucelosomes of the ``beads on a string'' structure. In mammalian cells, phosphohistone H3 is negligible during interphase but reaches a maximum for chromatin condensation during mitosis. Phosphohistone-H3 can serve as a mitotic marker to separate mitotic figures from apoptotic bodies and karyorrhectic debris, which may be a very useful tool in diagnosis of tumor grades, especially in CNS, skin, Gyn., soft tissue, and GIST.
ImmunogenImmunogen: A synthetic peptide corresponding to Human Histone H3 aa 1-100 (phospho S28) conjugated to Keyhole Limpet Haemocyanin (KLH). Specimen Preparation: Paraffin sections:. The antibody can be used on formalin-fixed paraffin-embedded (FFPE) tissue sections. Ensure tissue undergoes appropriate fixation to ensure best results. Pre-treatment of tissues with heat-induced epitope retrieval (HIER) is recommended using Bio SB ImmunoDNA Retriever with Citrate , ImmunoDNA Retriever with EDTA or Imm
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS373045
Price$130, $150, $170
Order / More InfoHistone H3 Phospho Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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