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Antigenic Specificity | MARCH1 (Internal) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes endogenous levels of 42064 protein. E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes viamultivesicular bodies. By constitutively ubiquitinating MHC class IIproteins in immature dendritic cells, down-regulates their cell surfacelocalization thus sequestering them in the intracellular endosomalsystem. |
Immunogen | Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the central region of human 42064. Conjugation: Unconjugated |
Other Names | [Rabbit (IgG) to Human MARCH1; MARCH1; MARCH-I; RING finger protein 171; RNF171] |
Gene, Accession # | [MARCH1], Gene ID: 55016, NCBI: NP_060393.1, UniProt: Q8TCQ1 |
Catalog # | MBS2401774 |
Price | $530 |
Order / More Info | MARCH1 (Internal) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |