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Antigenic Specificity | Apaf1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This monoclonal antibody is directed against human Apaf1 protein. The product was purified from Ascites by protein A chromatography. Expect reactivity with human, mouse and rat Apaf1. Cross-reactivity with Apaf1 from other sources has not been determined. Apoptosis is related to many diseases and is induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. The mammalian homologue of the key cell death gene CED-4 in C. elegans was identified recently from human and mouse and designated Apaf1 for apoptosis protease-activating factor 1. Apaf1 binds to cytochrome c (Apaf2) and caspase-9 (Apaf3), which leads to casp |
Immunogen | Immunogen: This protein A purified monoclonal antibody was prepared using conventional hybridoma technology after repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human Apaf1 protein. |
Other Names | [apoptotic protease-activating factor 1 isoform c; Apoptotic protease-activating factor 1; apoptotic protease-activating factor 1; apoptotic peptidase activating factor 1] |
Gene, Accession # | [Apaf1], Gene ID: 317, UniProt: O14727 |
Catalog # | MBS4156954 |
Price | $540 |
Order / More Info | Apaf1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |