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Antigenic Specificity | NR1H2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nuclear receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920). |
Immunogen | Immunogen: Recombinant human Oxysterols receptor LXR-beta protein |
Other Names | [Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuc; NR1H2; LXRB; NER; UNR] |
Gene, Accession # | [NR1H2], Gene ID: 7376, NCBI: NP_001243576.1, UniProt: P55055 |
Catalog # | MBS7044592 |
Price | $160, $235 |
Order / More Info | NR1H2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |