CAND1 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCAND1 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionKey assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjugation: in the deneddylated state, cullin-binding CAND1 binds CUL1-RBX1, increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human CAND1
Other Names[cullin-associated NEDD8-dissociated protein 1 isoform 1; Cullin-associated NEDD8-dissociated protein 1; cullin-associated NEDD8-dissociated protein 1; cullin associated and neddylation dissociated 1; Cullin-associated and neddylation-dissociated protein 1; TBP-interacting protein of 120 kDa A; TBP-interacting protein 120A; p120 CAND1]
Gene, Accession #[CAND1], Gene ID: 55832, NCBI: NP_060918.2, UniProt: Q86VP6
Catalog #MBS3219681
Price$335
Order / More InfoCAND1 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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