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Antigenic Specificity | Thioredoxin Reductase 1 (19A1) |
Clone | [19A1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG 1 |
Format | ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal Antibody to detect thioredoxin reductase I in human samples. Background: The mammalian thioredoxin reductases (TrxRs) are a family of seleno-cysteine containing pyridine nucleotide-disulfide oxido-reductases. All the mammalian TrxRs are homologous to glutathione reductase with respect to primary structure including the conserved redox catalytic site (-Cys-Val-Asn-Val-Gly-Cys-) but distinctively with a C-terminal extension containing a catalytically active penultimate seleno-cysteine (SeCys) residue in the conserved sequence(-Gly-Cys-SeCys-Gly). TrxR is homodimeric protein in which each monomer includes an FAD prosthetic group, a NADPH binding site and a redox catalytic site. Electrons are transferred from NADPH via FAD and the ac |
Immunogen | Immunogen: Recombinant human protein purified from E.coli. Positive Control: WB analysis of HeLa and Jurkat cell lysates. |
Other Names | [Thioredoxin Reductase; GRIM-12; MGC9145; TR; TR1; TRXR1; TXNR.], [TXNRD1; TXNRD1; TR; TR1; TXNR; TRXR1; GRIM-12; GRIM12; KDRF; TR; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein] |
Gene, Accession # | Gene ID: 7296, NCBI: NP_001087240.1, UniProt: Q16881 |
Catalog # | MBS840009 |
Price | $375 |
Order / More Info | Thioredoxin Reductase 1 (19A1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |