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Antigenic Specificity | Erk1/2 |
Clone | [784CT7.6.3] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.36 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged Erk1/2 protein was used to produced this monoclonal antibody. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The the MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in diffe |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1; MAPK3; ERK1; PRKM3] |
Gene, Accession # | [MAPK3], Gene ID: 5595, NCBI: NP_001035145.1, UniProt: P27361 |
Catalog # | MBS9200295 |
Price | $165, $370 |
Order / More Info | Erk1/2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sano H., et al. J. Biol. Chem. 277:19439-19447(2002). Ronnstrand L., et al. Cell. Mol. Life Sci. 61:2535-2548(2004). Charest D.L., et al. Mol. Cell. Biol. 13:4679-4690(1993). Aebersold D.M., et al. Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases. Cheng H., et al. Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases. |