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Antigenic Specificity | NR1I2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, |
Immunogen | Immunogen: Recombinant protein of human NR1I2 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [BXR; PAR; PRR; PXR; SAR; SXR; ONR1; PAR1; PAR2; PARq] |
Gene, Accession # | [NR1I2], Gene ID: 8856, NCBI: NP_003880.3, UniProt: O75469 |
Catalog # | MBS8527406 |
Price | $310 |
Order / More Info | NR1I2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |